Among these, vitamin D has been shown to alleviate several morbidities, including bacterial infections caused by Mycobacterium tuberculosis and S. aureus [8, 18, 19, 20, 21, 22]. In addition, vitamin D has been shown to support clearance of P.
Previous investigations revealed that vitamin D plays important roles in signaling in both the adaptive and innate immune response to viral and bacterial infection [16,25]. Vitamin D modulates the production of many cytokines, such as IL-2, IL-4, IL-6, IL-10, and IFN-γ [26-28].
Thus, vitamin C possesses potent antimicrobial properties reducing pathogenicity of bacteria, viruses, parasites, and fungi.
Vitamin D deficiency increases the risk of bacterial vaginosis during pregnancy: Evidence from a meta-analysis based on observational studies. Background: Bacterial vaginosis (BV) is the most common microbiological syndrome in women of childbearing age, causing numerous adverse health issues in pregnant women.
Vitamin D, acting in an intracrine fashion, is able to induce expression of antibacterial proteins and enhance the environment in which they function. The net effect of these actions is to support increased bacterial killing in a variety of cell types.
It's vital to bone health, muscle movement, nerve connections to the brain, and immune system function. Studies suggest vitamin D also may help protect us from infections (including COVID) and major diseases like cancer, cardiovascular and respiratory diseases, diabetes, and dementia.
It has been confirmed that vitamin D has potent anti-inflammatory properties. It contributes to reduction in pro-inflammatory mediators and an increase in anti-inflammatory cytokines. There is also evidence that vitamin D could decrease C-reactive protein (CRP) and affect selected haematological indices.
IRAK-4 deficiency is an inherited disorder of the immune system (primary immunodeficiency). This immunodeficiency leads to recurrent infections by a subset of bacteria known as pyogenic bacteria but not by other infectious agents.
In addition, probiotics might have synergistic effects with vitamin D, through improving the expression of vitamin D receptors [9]. Therefore, modulating the microbiota-gut-brain axis by probiotics plus improving vitamin D levels might provide a novel target to treat mental and metabolic disorders.
Abstract. The recent discovery that vitamin D regulates expression of the cathelicidin antimicrobial peptide gene has generated renewed interest in using vitamin D to fight infectious diseases.
Therefore, B vitamins are essential not only for the host but also for the bacteria living in the gut.
Consuming foods high in vitamin C such as grapefruits, oranges, tangerines, sweet red pepper, broccoli, strawberries, kale, and kiwifruit are thought to increase white blood cell production, which is key to fighting infection.
Vitamin D is also involved in innate and adaptive immunity, intestinal barrier integrity, and gut homeostasis. Vitamin D regulates the gut microbiota because vitamin D deficiency causes a microbial imbalance in the GIT. Vitamin D's antibacterial effect is linked to the expression of antimicrobial peptides (AMPs).
“We know that vitamin D plays a role in our immune system and our body's ability to fight off infection; we know that there are vitamin D receptors on immune cells and that vitamin D deficiency increases our susceptibility to infection,” says Byrn.
Some repeat infections, like pneumonia and bladder infections, may happen because of a genetic predisposition. That's an inherited tendency to get more infections than most people do. Structural issues. Repeat infections can also happen as a result of how your body is put together.
“Adding an over-the-counter vitamin D supplement can make improvements in just three to four months time.
Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures (broken bones). Severe vitamin D deficiency can also lead to other diseases: In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend.
1. Omega-3 fatty acids. Omega-3 fatty acids , which are abundant in fatty fish such as salmon or tuna, are among the most potent anti-inflammatory supplements. These supplements may help fight several types of inflammation, including vascular inflammation.
Vitamin D can modulate the innate and adaptive immune responses. Deficiency in vitamin D is associated with increased autoimmunity and an increased susceptibility to infection.