Calcium seems to have two opposing effects on histamine secretion from mast cells. A rise in the cytosol calcium concentration initiates the chain of reactions leading to histamine secretion. On the other hand, calcium appears to have a regulatory role, limiting the secretion.
Diamine oxidase (DAO) supplements are over-the-counter products that restore the diamine oxidase enzyme in your body. They help break down histamine-rich foods and may reduce symptoms of histamine intolerance.
Drinking plenty of water every day is essential for all bodily functions, including the regulation of histamine levels. Water does aid in the removal of histamines from the body as more that 95% of excess histamines are removed from the body through the urine.
Vitamin D3 provides support for a variety of body systems. This support is important for those who suffer from histamine intolerance, which also impacts a variety of body systems.
The zinc chelator N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) inhibits the release of histamine, the production of cytokines, and the secretion of lipid mediators in mast cells, and zinc supplementation rescues these inhibitory effects.
Studies suggest that vitamin B12 can trigger histamine release in the body. Certain bacteria or yeasts can convert histidine into histamine in the body, triggering an allergic reaction. Fermented foods high in certain types of microorganisms can trigger a histamine allergy in the body.
Natural antihistamines may help you control your seasonal allergies. Common ones are stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics. Some alternative practices—such as acupuncture, nasal irrigation, and exercise—may also help you manage symptoms.
The intake of Omega-3 Total is unproblematic. Due to the poor fat solubility of histamine, professionally produced fish oil is harmless with regard to histamine and therefore has no side effects for people with histamine intolerance.
Vitamin C. Good old vitamin C is another basic, yet powerful supplement that can decrease histamine and relieve intolerance symptoms. Vitamin C can help you produce more of the DAO enzyme to break down histamine. Plus, it's a powerful antioxidant that can reduce inflammation throughout the body.
There is currently no cure for histamine intolerance. The key to success is for the patient to learn to adjust to a low-histamine diet and manage the condition(s) until it either goes away, or for life. The patient needs to avoid stress.
Managing a histamine intolerance tends to involve making dietary changes, taking antihistamines or enzyme supplements, and avoiding or limiting the use of medications that trigger the release of histamine.
Extra virgin olive oil can actually help to increase DAO levels in the body, which can aid in reducing histamine intolerance symptoms.
Lavender Essential Oil works as a natural antihistamine and possesses strong anti-inflammatory properties that will treat an relieve most allergic reactions. Peppermint Essential Oil is strong, fresh and minty and opens clogged sinuses almost immediately.
Coffee contains histamines in low amounts, but for people who are sensitive to them, it contains plenty to get a reaction out of them. While the natural histamine content in coffee is low, some coffee processes can increase histamine levels.
Boswellia, also known as frankincense, is a potent anti-inflammatory herbal medicine that can help to stabalise mast cells and reduce histamine load in the body.
High Histamine Foods
Fruit: Citrus fruits, strawberries, bananas, pineapple, pears.
Another significant link between B6 and histamine intolerance, is B6's role in supporting DAOs function to break down histamine. When vitamin B6 is too low, DAO cannot be produced effectively, as B6 plays an important role in the process of DAO formation(3,4,5).
Vitamin B6 is essential for healthy skin and a normal functioning immune system. It is a natural antihistamine with the ability to reduce histamine intolerance (along with vitamin C), making it helpful for people with allergies and histamine intolerance.
Folate is an important part of the methylation cycle. The key point to remember is that folate, even methyl-folate, is a net methyl reducer. Reducing methyl is key because that will cause histamine to increase. Histamine is an important messenger and neurotransmitter in the body.
Magnesium is a mineral that relieves the constriction of the airways in the lungs. It's been found that magnesium deficiency can cause an increase in histamine levels in the blood after being exposed to allergens.
Probiotics are one of the most essential supplements for healing histamine intolerance.
Therefore, Co-Q10 can control inflammation in airway and allergic reactions in upper and lower airways and modulate immune response in lung. This treatment significantly controls IgE, histamine, Cyc-LT and LTB4 as main allergic bio-factors and allergic response mediators.