Jeffrey Blumberg, a professor of nutrition science and policy at Tufts University in Boston, says otherwise. He suggests taking your dietary supplements at night isn't advisable. “Digestion slows down during sleep, so taking your nutrient supplement late at night would not be associated with an efficient absorption.”
However, taking a multivitamin too close to bedtime could actually interfere with your ability to fall asleep. Many vitamin formulas contain energizing ingredients that encourage your body to be alert and awake when taken too late in the day.
More research is needed to determine how multivitamins affect your sleep, if they do at all, and whether the time of day you take them can impact this. There just isn't enough information to recommend avoiding multivitamins at night, so you can take them whenever you find it most convenient.
Certain vitamins, like those believed to aid in supporting your energy levels, may actually interfere with your sleep if you take them too close to bedtime, and on the other hand, some vitamins can help promote a deeper, more restful sleep.
There isn't any available scientific research showing that taking your vitamins in the morning, at noon or before bed makes any difference in how they are absorbed or used by the body.
So, get enough vitamin D—just take it in the morning or afternoon. At night, take supplements that support sleep quality and muscle relaxation, like magnesium and melatonin (which you'll find in soothing, sippable Bulletproof Sleep Collagen Protein).
Magnesium and calcium/multivitamin
But if you do take magnesium, Erin Stokes, ND, recommends not taking it at the same time as your multivitamin, as it may interfere with the absorption of smaller minerals found in the multivitamin, like iron and zinc.
Magnesium can decrease the absorption and effectiveness of numerous medications, including some common antibiotics such as tetracycline (Achromycin, Sumycin), demeclocycline (Declomycin), doxycycline (Vibramycin), minocycline (Minocin), ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Avelox) and ofloxacin ...
One study of older adults with insomnia found that magnesium supplementation at a dose of 500 milligrams daily for eight weeks helped them fall asleep faster, stay asleep longer, reduced nighttime awakenings, and increased their levels of naturally circulating melatonin.
However, the time of day you take them doesn't matter much. Many people have no need to supplement with these vitamins in large doses. Taking too much of some vitamins can cause more harm than good. Additionally, some vitamins (such as vitamin K) may interfere with medications.
Therefore, magnesium supplements can be taken at any time of the day, as long as you're able to take them consistently. For some, taking supplements first thing in the morning may be easiest, while others may find that taking them with dinner or just before bed works well for them.
You can—but it's probably not a good idea. For some supplements, optimal absorption can depend on the time of day taken. Not only that—taking certain vitamins, minerals, or other supplements together can also reduce absorption and may result in adverse interactions, which can be harmful to your health.
You can take a multivitamin at night, as long as you take it with a small bit of food to coat your stomach and to help your body absorb the fat-soluble vitamins.
It Can Help Your Body and Brain Relax
In order to fall asleep and stay asleep, your body and brain need to relax. On a chemical level, magnesium aids this process by activating the parasympathetic nervous system, the system responsible for getting you calm and relaxed ( 6 ).
Some studies have found that magnesium supplements can: Make it easier to fall asleep. Improve sleep quality. Reduce symptoms of restless legs syndrome, which can interfere with a good night's sleep.
The use of chemicals, such as fluoride and chlorine, bind to magnesium, making the water supply low in the mineral, as well. Common substances — such as sugar and caffeine — deplete the body's magnesium levels.
People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.
Magnesium supplementation has been used successfully in the treatment of different conditions such as PMS, PCOS, mood disorders, and postmenopausal symptoms and consequent risk factors, particularly in the association with other dietary components with proven antioxidant and anti-inflammatory activity.
Magnesium and zinc
All minerals and vitamins need the proper conditions for your body to absorb them properly. When taken together, magnesium and zinc have mutual benefits. Magnesium helps your body regulate its zinc levels, while zinc does the job of allowing it to absorb magnesium more effectively.
Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.