Symptoms of neuropathy usually stop when the supplements are discontinued. High-dose vitamin B supplements should be avoided, because they can lead to nerve damage.
pins and needles (paraesthesia) loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking. damage to parts of the nervous system (peripheral neuropathy), particularly in the legs.
Tingling sensation or Numbness
This symptom is one of the early warning indicators of Vitamin B12 overdose.
B12 deficiency may cause demyelination of nerves in the peripheral and central nervous system13 and has been associated with peripheral neuropathy, loss of sensation in peripheral nerves, and weakness in lower extremities in older adults1, 14–16.
To much b-12 can aggravate the nerves.
Vitamin B12 is a water-soluble vitamin, and the risks of dose-related side effects are low. Your body can usually get rid of excess vitamin B12 through your urine. In rare cases, high doses of vitamin B12 injections have been associated with skin reactions. This isn't the case for oral vitamin B12 dietary supplements.
Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment.
Conclusion: This observation demonstrates that, in spite of its poor outcome reported by several authors, peripheral neuropathy induced by vitamin B12 deficiency can recover completely with substitutive treatment.
It's unclear whether taking vitamin B-12 supplements can help treat diabetic neuropathy. Some small studies have shown a lessening of pain and other abnormal sensations. However, for people who don't have a vitamin B-12 deficiency, taking B-12 supplements for diabetic neuropathy hasn't been shown to help.
Many people are not aware that vitamin B6 can cause peripheral neuropathy, which results in tingling, burning or numbness usually in the hands and feet. Taking vitamin B6 even at low doses can cause peripheral neuropathy but people are more likely to get it if they are taking more than one supplement.
Vitamin B12deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet. difficulty walking (staggering, balance problems)
Paresthesia is a medical term that refers to a burning or pins-and-needles sensation in certain areas of the body, like the hands and feet. Many adults and kids who have B12 deficiency report experiencing paresthesia ( 7 , 20 ).
Nutritional or vitamin imbalances, alcoholism, and exposure to toxins can damage nerves and cause neuropathy. Vitamin B12 deficiency and excess vitamin B6 are the best known vitamin-related causes. Several medications have been shown to occasionally cause neuropathy.
Confirming if you have a neuropathy
a nerve conduction test (NCS), where small metal wires called electrodes are placed on your skin that release tiny electric shocks to stimulate your nerves; the speed and strength of the nerve signal is measured.
Regular exercise, such as walking three times a week, can reduce neuropathy pain, improve muscle strength and help control blood sugar levels. Gentle routines such as yoga and tai chi might also help.
B vitamins are useful in treating neuropathy since they support healthy nervous system function. Peripheral neuropathy is sometimes caused by a vitamin B deficiency. Supplementation should include vitamin B1 (thiamine and benfotiamine), B6, and B12.
The symptoms of peripheral neuropathy may lessen or go away over time, but in some cases they never go away. These are some ways to learn to live with it: Use pain medicines as your doctor prescribes them.
There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.
However, in routine laboratory practice serum vitamin B12 (B12) levels are more often above than below normal. Supraphysiological serum B12 levels may result from high dose supplementation, more often, however, they are due to increased levels of the sequestered form of the vitamin.
Vitamin B12 deficiency can cause paresthesia, peripheral neuropathy, and a serious irreversible deficiency disease known as subacute combined degeneration of the spinal cord, with demyelination damage to both the corticospinal and dorsal columns of the spinal tract. Weakness and gait impairment may result.
Vitamins B-1, B-6, and B-12 have been found to be especially beneficial for treating neuropathy. Vitamin B-1, also known as thiamine, helps to reduce pain and inflammation and vitamin B-6 preserves the covering on nerve endings.
Pantothenic acid deficiency has historically been associated with the severe clinical presentation seen in burning feet syndrome,6 which was first described in Japanese prison camps during the Second World War.