Yes, a lack of vitamin B12 can directly cause severe joint pain, often alongside neurological symptoms like tingling, numbness, and weakness, due to its role in nerve health, red blood cell production, and inflammation regulation (specifically by affecting homocysteine levels). Deficiency can lead to nerve damage (neuropathy) that feels like joint pain or exacerbates existing joint issues, making B12 deficiency a potential, though sometimes overlooked, cause of joint discomfort.
Vitamin B12 deficiency can also cause symptoms that affect your brain and nervous system (neurological symptoms), including: numbness. muscle weakness. psychological problems, which can range from mild depression or anxiety, to confusion and dementia.
No direct, significant interactions are widely reported between Vitamin B12 and amlodipine, but it's crucial to consult your doctor because general vitamin supplements (especially multivitamins with minerals) can affect blood pressure medications, potentially reducing amlodipine's effectiveness, and your healthcare provider knows your full health picture. Always discuss all supplements with your doctor before combining them with amlodipine.
Hydroxocobalamin and pregnancy
Hydroxocobalamin can be used during pregnancy. It's important that a vitamin B12 deficiency is correctly treated to make sure that you and your baby are healthy.
In our experience, oral spray supplements can take 3 days to increase serum nutrient levels, with a significant increase seen after 10 days, and a deficiency can be turned into an optimal level within 10 weeks.
Two common types of GERD medicines have been linked to vitamin B-12 deficiency:
During pregnancy, ensuring adequate vitamin B12 levels is crucial for fetal development and maternal health. The third trimester is especially significant as the fetus undergoes rapid growth and development, necessitating adequate nutrient transfer from the mother.
To make sure it's safe for you, tell your doctor before having hydroxocobalamin if you:
If you're pregnant, not having enough vitamin B12 can increase the risk of your baby developing a serious birth defect known as a neural tube defect.
Common side effects
Vitamin B12 itself is vital for energy production, red blood cell formation, and nerve function. Typically, B12 cocktails include a mix of B12 injections or supplements, coconut water, citrus fruits, and other natural ingredients known to aid in weight management.
CALCIUM CHANNEL BLOCKERS
Examples include; amlodipine, nifedipine, felodipine, diltiazem and verapamil. Nutrients that can be depleted by these medicines are potassium, calcium, vitamin D and possibly Co-Enzyme Q10.
B12 deficiency can trigger specific food cravings, most notably for meat, fish, or eggs, as the body seeks animal-based sources to replenish the vitamin, especially in those on vegetarian/vegan diets or older adults. While cravings for sugary or salty foods can also signal general B-vitamin issues, the distinct urge for protein-rich animal products is a key indicator, but professional testing is crucial for confirmation.
Cutaneous manifestations associated with vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes. A diagnosis of vitamin B12 deficiency is often overlooked in its early stages because these signs are not specific to vitamin B12 deficiency alone.
You might want to investigate a B12 deficiency if you are experiencing foot pain or lower limb pain. Vitamin B12 is an essential nutrient, primarily found in animal products, that plays a key role in maintaining nerve function, producing red blood cells, and synthesizing DNA.
Your doctor likely stopped B12 injections due to following standard guidelines suggesting oral supplements or for reasons like cost/logistics (especially during the pandemic), but this can be risky; the main reasons are often a perceived 'normal' blood test (which doesn't always reflect cell levels) or a guideline shift, but you may still need injections for neurological symptoms or poor absorption, so discuss your symptoms urgently with your doctor and ask for clear evidence for the change.
Possible interactions include:
In addition to fatigue, a deficiency of B12 can lead to other symptoms like pale skin, headaches, depression, gastrointestinal problems, difficulty concentrating, decreased mental function, mouth and tongue pain or inflammation, and paresthesia in your hands and feet.
Symptoms of vitamin B12 or folate deficiency
Vitamin B12 doesn't directly cure plantar fasciitis, but a deficiency can worsen symptoms or mimic it by causing nerve issues (neuropathy) and weakening tissues, while supplementing may help if you're deficient by improving nerve health and healing, though the primary treatment remains stretching, orthotics, and rest to address the mechanical stress.
A normal level of vitamin B12 in your bloodstream is 160-950 picograms per milliliter (pg/mL). Between 200 and 300 pg/mL is considered borderline. Your doctor may do more tests. Below 200 pg/mL is low.
There is general consensus that gastric acid–lowering drugs, including proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs), and the antidiabetes drug metformin can reduce circulating vitamin B-12 concentrations with prolonged use.
Vitamin B12 deficiency can cause physical, neurological and psychological symptoms. Physical symptoms can include: Feeling very tired or weak. Experiencing nausea, vomiting or diarrhea.
In fact, some studies have even suggested the opposite. For instance, one study noted that individuals who regularly took vitamin B12 supplements gained between 2.5 to 17 fewer pounds (1.2 to 7.7 kg) over a decade than those who didn't supplement.