No interactions were found between Calcium, Magnesium and Zinc and Vitamin D3.
People considering starting a Vitamin D3 regimen without the advice of a doctor should consider supplementing with magnesium as well to prevent the adverse effects of unabsorbed calcium.
Try taking it alongside breakfast or with a bedtime snack — as long as it doesn't interfere with your sleep. The key is to find what works for you and stick with it to ensure you're meeting your vitamin D needs. Taking vitamin D with a meal can increase its absorption, but studies on specific timing are limited.
Taking high levels of zinc (142 milligrams a day and up) in supplement form may interfere with magnesium absorption. If you are taking zinc at extremely high doses due to medical issues, take the zinc several hours before or after taking a magnesium supplement.
They can work together, boosting and enhancing absorption, or sometimes work against each other, competing for absorption. Zinc and magnesium are synergistic minerals that work together when taken at the right dosages.
Yes! You can and should take magnesium and vitamin D together. In fact, the bioavailability of vitamin D largely relies on magnesium. Also, many nutrients wouldn't work efficiently without magnesium, further highlighting the importance of this mineral!
Do not take zinc supplements and copper, iron, or phosphorus supplements at the same time. It is best to space doses of these products 2 hours apart, to get the full benefit from each dietary supplement.
Take-away: Calcium and magnesium may best be taken in the evening with food or before nighttime sleep. Since zinc should not be taken with calcium and apart from iron, it is most useful if taken earlier in the day either slightly before/after food.
Dosage guidelines generally state that you should take 2–3 calcium-magnesium-zinc supplements daily. However, supplementing isn't necessary if you get enough of these nutrients through your diet.
Zinc. Zinc is often part of multivitamins but is also taken alone or in combination with vitamin C. Its absorption is most effective on an empty stomach, but it can cause stomach upsets. In this case it should be taken with a meal and therefore not late at night.
Magnesium and calcium/multivitamin
But if you do take magnesium, Erin Stokes, ND, recommends not taking it at the same time as your multivitamin, as it may interfere with the absorption of smaller minerals found in the multivitamin, like iron and zinc.
And if you're routinely consuming refined grains in lieu of whole grains, you may be short on dietary magnesium, which ultimately affects your vitamin D levels. If you choose to supplement with magnesium, "taking less than 300 mg of magnesium for men and 270 mg for women is generally recommended," Sasse says.
We recommend taking it with a source of quality fat in the morning or when you break your fast. Avoid taking vitamin D in the evening (we'll talk about why below). Since vitamin D is a fat-soluble vitamin—meaning it doesn't dissolve in water—your body can most easily absorb it when you take it with food.
Interactions. Possible interactions include: Aluminum. Taking vitamin D and aluminum-containing phosphate binders, which may be used to treat high serum phosphate levels in people with chronic kidney disease, might cause harmful levels of aluminum in people with kidney failure in the long term.
Phenobarbital, phenytoin, and other anticonvulsant medications -- These medications may accelerate the body's use of vitamin D. Mineral oil -- Mineral oil also interferes with absorption. In addition, Vitamin D may enhance the effects of doxorubicin , a medicine used to treat a variety of cancers.
Summary: Vitamin D can't be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50 percent of Americans. In addition, Vitamin D supplements can increase a person's calcium and phosphate levels even while they remain Vitamin D deficient.
The combination of zinc and magnesium may improve your sleep quality. Research suggests that magnesium helps activate the parasympathetic nervous system, which is responsible for helping your body feel calm and relaxed ( 28 , 29 ).
Zinc supports your immune system and muscles. Magnesium plays a role in metabolism and muscle health and helps manage sleep. B6 may boost energy. ZMA makers claim that increasing these three nutrients in your system can build muscle strength and stamina, speed muscle recovery, and improve the quality of your sleep.
How to use Vitamin D3. Take vitamin D by mouth as directed. Vitamin D is best absorbed when taken after a meal but may be taken with or without food.
If you're looking to get more vitamin D in your diet, take it with a side of magnesium. That mineral appears to help regulate levels of vitamin D, which in turn manages the levels of other minerals such as calcium and phosphorus.
Some foods can block the absorption of magnesium, for example, high protein diets can decrease magnesium absorption. Tannins in tea bind and remove minerals including magnesium. Oxalic acid in rhubarb, spinach and chard and phytic acid in cereals and soy also block the absorption of magnesium.
VITAMIN C+VITAMIN D3+ZINC is likely safe to consume. In some cases, it may cause side effects like diarrhoea, nausea, and vomiting. These side effects are not common to everyone and usually do not require medical attention. However, if these side effects persist longer, please consult your doctor.
The vitamin D receptor (VDR) binds zinc, and the activity of vitamin D dependent genes in cells is influenced by intracellular zinc concentrations. Zinc help vitamin D to work inside the cells. It is also important to ensure that the calcium from foods or supplements is used in your bones.
But taking doses higher than 40 mg daily might decrease how much copper the body absorbs. Taking very high doses of zinc is likely unsafe and might cause stomach pain, vomiting, and many other problems. Single doses of 10-30 grams of zinc can be fatal.