These high blood pressure medications control nerve impulses, relaxing blood vessels. Central agonists may cause: Anemia. Constipation.
Antihypertensive medication use can be associated with a reduction in hemoglobin concentration. The magnitude of such a change is generally small, but in certain instances it can be extreme enough to produce a clinically significant degree of anemia.
Anemia is associated with higher cardiovascular risk, higher blood pressure values, and lower dipping status in hypertensive patients, and hemoglobin should be monitored in hypertensive patients.
Possible causes of anemia include: Iron deficiency. Vitamin B12 deficiency. Folate deficiency. Certain medicines.
The anemia itself can worsen cardiac function, both because it causes cardiac stress through tachycardia and increased stroke volume, and because it can cause a reduced renal blood flow and fluid retention, adding further stress to the heart.
Drugs like Cephalosporins, Dapsone, Levodopa, Nonsteroidal anti-inflammatory drugs (NSAIDs), Penicillin and its derivatives, etc, must be avoided as they may cause hemolytic anaemia. Always consult with your doctor before taking these medications.
Undiagnosed or untreated iron-deficiency anemia may cause serious complications such as fatigue, headaches, restless legs syndrome, heart problems, pregnancy complications, and developmental delays in children. Iron-deficiency anemia can also make other chronic conditions worse or cause their treatments to work poorly.
Several types of medication can lead to an immune response that causes drug-induced anemia. Cephalosporins, a class of antibiotics, is the most common cause of the condition. Other medications that may cause drug-induced anemia include the following: Other antibiotics, such as penicillin or levofloxacin.
Your healthcare provider may decide to lower your dose — or stop your medication completely — if your blood pressure has been well-controlled for some time, typically after at least 1 year.
Safe medications to use include methyldopa and potentially some diuretics and beta-blockers, including labetalol.
Fatigue. Tiring easily, and waking up tired even after a good night's sleep, are common and potentially serious symptoms of anemia. This is due to reduced and compromised red blood cells that naturally cannot carry the required levels of oxygen to the organs – which, in turn, cannot function efficiently.
Stage 1: Diminished total-body iron content. Stage 2: Reduced red blood cell formation. Stage 3: Iron deficiency anemia.
Severe iron deficiency anaemia may increase your risk of developing complications that affect the heart or lungs, such as an abnormally fast heartbeat (tachycardia) or heart failure, where your heart is unable to pump enough blood around your body at the right pressure.
Mild anemia is a common and treatable condition that can develop in anyone. It may come about suddenly or over time, and may be caused by your diet, medicines you take, or another medical condition. Anemia can also be chronic, meaning it lasts a long time and may never go away completely.
Lifestyle habits: People who do not get nutrients like iron, vitamin B12, and folic acid to make healthy red blood cells have a higher risk of anemia. 2 Drinking too much alcohol also raises your risk of anemia.
Don't change or stop taking your medication without first talking to your care provider. If it's not clear what's causing low blood pressure or no treatment exists, the goal is to raise blood pressure and reduce symptoms.
How they can cause fatigue: Blood-pressure medications may slow down the pumping action of the heart as well as depress the entire central nervous system, or, in the case of diuretics, deplete electrolytes that the body needs.
While the class of blood pressure-lowering medicines called angiotensin-converting enzyme (ACE) inhibitors may be prescribed more commonly, angiotensin receptor blockers (ARBs) work just as well and may cause fewer side effects.