Any malformations in the uterus can result in recurrent implantation failure. Some individuals are born with anatomically different uteruses while other problems can be acquired during one's lifetime. These include uterine fibroids and other issues that can impact your uterine health.
Unfortunately, various conditions can hamper the proper implantation of a blastocyst. In some cases, genetic disorders in the developing embryo disrupt the trypsin signal and cause a stress reaction that forces the uterus to reject the blastocyst.
The causes of implantation failure are diverse and especially due to different maternal factors as uterine abnormalities, hormonal or metabolic disorders, infections, immunological factors, thrombophilias as well as other less common ones.
It's recommended that you avoid strenuous physical activities like heavy weight-lifting or high-impact cardio during your two-week wait as it could lead to uterine contractions and affect the implantation process. After the first few days of our waiting period, you can do some light exercising like walking or swimming.
Implantation failure is related to either maternal factors or embryonic causes. Maternal factors include uterine anatomic abnormalities, thrombophilia, non-receptive endometrium and immunological factors.
In some cases, a woman may experience light spotting or cramping around the time when implantation would have occurred, but these symptoms can also be a sign of a normal menstrual cycle. One potential indicator of failed implantation is changes in basal body temperature.
During the two-week wait, it's better to err on the side of caution. Avoid having a drink, smoking, or any other activity that could be harmful to a brand new pregnancy. It's fine to continue exercising if you already have a workout routine, but now might not be the time to take up a new, intense form of exercise.
Certain lifestyle habits may create an environment that supports implantation. This includes eating a healthy diet, managing stress, and checking your progesterone. Progesterone medications are often prescribed for women undergoing IVF treatments. This increases the chances of successful implantation.
Mechanistically, caffeine-induced implantation failure could be partially ascribed to delayed oviductal embryo transport, as preimplantation caffeine exposure can result in embryo retention in the isthmus of the fallopian tube [35]; this in vivo observation is consistent with previous ex vivo data showing that caffeine ...
Lamppa says that the blastocyst usually implants in your uterine wall about 6 to 10 days after it's been fertilized by sperm. There's about a 12 to 24-hour window for fertilization to happen during ovulation.
When an embryo fails to implant, there can only be two logical reasons: the embryo is not good enough (genetically abnormal), or the endometrium is not “receptive” (doesn't allow the embryo to implant) enough.
Mental stress can lead to an increased endogenous level of epinephrine. Excessive epinephrine level may interfere with the decidual differentiation of human endometrial stromal cells and thus affect embryo implantation.
After it is in the uterus, a fertilized egg usually attaches to (implants in) the lining of the uterus (endometrium). But not all fertilized eggs successfully implant. If the egg is not fertilized or does not implant, the woman's body sheds the egg and the endometrium.
Even if a blastocyst has the potential to result in live birth, other factors can impact its ability to implant, including maternal factors (age, body mass index [BMI], and general health status), paternal factors (age and sperm quality), uterine factors (endometrial thickness, pattern, and compaction and uterine ...
Try to avoid caffeine during the two-week wait. 6) Avoid alcohol! Alcohol can also be harmful to your fertility and can affect your ability to conceive. It is best to avoid alcohol altogether during the two-week wait.
But the authors of the research in the BMJ concluded that women who are trying to conceive or already expecting a baby should avoid caffeine altogether. There's 'no safe level' according to their research.
Drinks with added sugar, like soda, lemonade, and sports and energy drinks are foods to avoid when trying to conceive.
Exercise mindfully
In these cases, walking and fertility yoga are two of the best ways to promote circulation and improve strength and flexibility of the muscles surrounding the uterus. Talk to your doctor about your unique health factors to determine an appropriate exercise regimen while trying to conceive.
“Medically, occasional alcohol consumption during this time period should not have any significant impact on implantation or pregnancy health—however, if having a drink and then finding out you have a positive pregnancy test is going to keep you up nights, best to abstain,” she says.
There's no evidence to show that any sleeping position is better than any other for embryo implantation. The embryo is transferred when your womb is ready, when the lining is soft and thick and ideal for an embryo to implant. You can lie however you like – just get comfy.
While you should rest, strict bed rest is no longer necessary or even advisable. Yet, there are still certain activities and precautions that should be taken after an embryo transfer to increase your odds of success.